As part of implementation of the Global Action Plan on Antimicrobial Resistance, WHO drew up a list of priority antibiotic-resistant pathogens (priority pathogens list; PPL) to guide research into and the discovery and development of new antibiotics. As a further step, WHO reviewed the publicly available information on the current clinical development pipeline of antibacterial agents to assess the extent to which the drug candidates act against these priority pathogens, Mycobacterium tuberculosis, and Clostridium difficile.
The review shows that the current clinical pipeline is still insufficient to mitigate the threat of antimicrobial resistance.
To read this report in full: http://apps.who.int/iris/bitstream/10665/258965/1/WHO-EMP-IAU-2017.11-eng.pdf?ua=1
The EU and the Food and Agriculture Organisation of the United Nations join forces to take action on food waste and antimicrobial resistance.
The Commissioner for Health and Food Safety Vytenis Andriukaitis and the Director-General of the Food and Agriculture Organisation of the United Nations (FAO) José Graziano da Silva, today agreed to ramp up collaboration between the two organisations in tackling the problems of waste in food supply chains and antimicrobial resistance.
The FAO and the EU pledge to work closely together to halve per capita food waste by 2030, a goal established under the new Sustainable Development Goals global agenda. It also commits them to intensified cooperation on tackling the spread of antimicrobial resistance (AMR) on farms and in food systems.
To read more about these initiatives on the European Commission website: http://europa.eu/rapid/press-release_IP-17-3561_en.htm
The European Commission adopted two legal acts aimed at improving patient safety in the EU through good manufacturing practices (GMP) that ensure the highest quality of medicines for human use.
The first act is an implementing directive that sets out principles and guidelines of GMP in medicines where the manufacture or import is subject to a manufacturing authorisation: see Article 40 of the Community code Directive (2001/83/EC).
The second act is a delegated regulation that sets out GMP for investigational medicinal products, as required by the Clinical Trials Regulation (536/2014/EU), and detailed arrangements for inspections. This legal act ensures the highest quality of medicinal products used in clinical trials and prepares the smooth entry into force of this Regulation.
To read more about this on the europa.eu website: http://ec.europa.eu/newsroom/sante/newsletter-specific-archive-issue.cfm?newsletter_service_id=327&newsletter_issue_id=5153
The German government’s Federal Ministry of Education and Research (BMBF) is dedicating up to EUR 500 million in the coming decade to support the G20’s international research initiative devoted to fighting antimicrobial resistance (AMR). The initiative was announced in the G20 leaders’ final declaration at the end of the G20 summit in July. The BMBF’s funding pledge came shortly afterwards.
Germany has played a decisive role in getting the AMR initiative up and running during its G20 presidency. Ahead of the summit in Hamburg, the country organised and held the first-ever meeting solely for G20 health ministers.
To read more about this initiative on the German Federal Ministry for Economic Affairs and Energy website: http://www.exportinitiative-gesundheitswirtschaft.de/EIG/Redaktion/EN/Kurzmeldungen/News/2017/2017-08-15-germany-promotes-g20-initiative-against-antimicrobial-resistance.html
European women’s probability of developing breast cancer over a lifetime is approximately 1 in 8*. A woman’s individual risk of breast cancer may be higher or lower than this average, depending on a number of factors, including age, family history, reproductive history (such as menstrual and childbearing history), race/ethnicity, and others.
The ECIBC is developing recommendations for breast cancer screening and diagnosis. Each recommendation is specifically tailored to the needs of citizens and patients, health professionals, and policy makers. All recommendations are based on the female population at ‘average’ and ‘below average’ risk of developing breast cancer.
To read more about this initiative on the Europa.eu site: http://ecibc.jrc.ec.europa.eu/recommendations/
In a recent study, screening rates for hepatitis C virus (HCV) infection among baby boomers increased fivefold in the year following implementation of an electronic health record (EHR)-based prompt for primary care physicians. The prompt also led to dramatic increases in follow-up specialised care for infected patients, according to the Hepatology study.
To read more: Electronic Health Record Alert Improves HCV Screening and Treatment
The World Health Organization (WHO) has updated its fact sheet on falls. Key facts include:
- Falls are the second leading cause of accidental or unintentional injury deaths worldwide.
- Each year an estimated 646 000 individuals die from falls globally of which over 80% are in low- and middle-income countries.
- Adults older than 65 years of age suffer the greatest number of fatal falls.
- 37.3 million falls that are severe enough to require medical attention occur each year.
- Prevention strategies should emphasize education, training, creating safer environments, prioritizing fall-related research and establishing effective policies to reduce risk.
To read more on the WHO website: http://www.who.int/mediacentre/factsheets/fs344/en/
Towards tobacco-free generations: stopping second-hand smoke and smoking initiation among children
Several Member States in the WHO European Region are moving towards becoming “tobacco-free”, which means having a smoking prevalence of 5% or less. To achieve this, countries must address a number of tobacco-related issues that specifically impact children, and work to protect children from the harmful effects of tobacco.
Second-hand exposure kills over 600 000 non-smokers globally each year, many of whom are children. Causes of such deaths include asthma, respiratory infections and cancer.
To read more about tobacco-free generations from euro.who.int: http://www.euro.who.int/en/health-topics/disease-prevention/tobacco/publications/2017/tobacco-free-generations-protecting-children-from-tobacco-in-the-who-european-region-2017
Further to the decision of the 140th session of the Executive Board to request the WHO Director-General to develop a draft global action plan to promote physical activity, the WHO Secretariat is hosting an open web-based consultation on a first draft from 1 August 2017 to 22 September 2017.
Physical inactivity is one of the leading behavioural risk factors for the leading causes of NCDs, namely heart disease, stroke, breast and colon cancers and diabetes. Conversely, regular physical activity is associated with improved well-being, as well as enhanced social and mental health. However, inactivity is on the rise in many countries, and globally one in four adults, and four out of five adolescents, do not meet the global recommendations.
Read the Draft WHO global action plan on physical activity 2018 – 2030 on the who.int website.
Malaria does not occur naturally in the UK but travel-associated cases are reported in those who have returned to the UK or arrived (either as a visitor or migrant to the UK) from malaria-endemic areas. An annual report has presented data on malaria imported into the UK, based on figures reported to Public Health England’s Malaria reference laboratory.
In 2016, 1,618 cases of imported malaria were reported in the UK (1,529 in England, 58 in Scotland, 25 in Wales and six in Northern Ireland), 15.6% higher than reported in 2015 (N=1,400) and 4.5% above the mean number of 1,547 cases reported between 2006 and 2015.
See the full document about Malaria in the UK on the gov.uk website.